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Synthetic PreImplantation Factor (sPIF) induces posttranslational protein modification and reverses paralysis in EAE mice

An autoimmune response against myelin protein is considered one of the key pathogenic processes that initiates multiple sclerosis (MS). The currently available MS disease modifying therapies have demonstrated to reduce the frequency of inflammatory attacks. However, they appear limited in preventing...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hayrabedyan, Soren, Shainer, Reut, Yekhtin, Zhanna, Weiss, Lola, Almogi-Hazan, Osnat, Or, Reuven, Farnsworth, Charles L., Newsome, Scott, Todorova, Krassimira, Paidas, Michael J., Brodie, Chaya, Barnea, Eytan R., Mueller, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775138/
https://ncbi.nlm.nih.gov/pubmed/31578341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48473-x
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