Synthetic PreImplantation Factor (sPIF) induces posttranslational protein modification and reverses paralysis in EAE mice

An autoimmune response against myelin protein is considered one of the key pathogenic processes that initiates multiple sclerosis (MS). The currently available MS disease modifying therapies have demonstrated to reduce the frequency of inflammatory attacks. However, they appear limited in preventing...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Hayrabedyan, Soren, Shainer, Reut, Yekhtin, Zhanna, Weiss, Lola, Almogi-Hazan, Osnat, Or, Reuven, Farnsworth, Charles L., Newsome, Scott, Todorova, Krassimira, Paidas, Michael J., Brodie, Chaya, Barnea, Eytan R., Mueller, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775138/
https://ncbi.nlm.nih.gov/pubmed/31578341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48473-x
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