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Significant lethality following liver resection in A20 heterozygous knockout mice uncovers a key role for A20 in liver regeneration

Hepatic expression of A20, including in hepatocytes, increases in response to injury, inflammation and resection. This increase likely serves a hepatoprotective purpose. The characteristic unfettered liver inflammation and necrosis in A20 knockout mice established physiologic upregulation of A20 as...

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Publicat a:Cell Death Differ
Autors principals: Studer, P, da Silva, C G, Revuelta Cervantes, J M, Mele, A, Csizmadia, E, Siracuse, J J, Damrauer, S M, Peterson, C R, Candinas, D, Stroka, D M, Ma, A, Bhasin, M, Ferran, C
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816110/
https://ncbi.nlm.nih.gov/pubmed/25976305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.52
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