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A20 Protects Mice from Lethal Liver Ischemia Reperfusion Injury by Increasing Peroxisome Proliferator-Activated Receptor-α Expression

The NF-κB inhibitory protein A20 demonstrates hepatoprotective abilities through combined anti-apoptotic, anti-inflammatory and pro-proliferative functions. Accordingly, overexpression of A20 in the liver protects mice from toxic hepatitis and lethal radical hepatectomy while A20 knockout mice die p...

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Detalhes bibliográficos
Main Authors: Ramsey, Haley E., Da Silva, Cleide G., Longo, Christopher R., Csizmadia, Eva, Studer, Peter, Patel, Virendra I., Damrauer, Scott M., Siracuse, Jeffrey J., Daniel, Soizic, Ferran, Christiane
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976064/
https://ncbi.nlm.nih.gov/pubmed/19877201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lt.21879
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