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Protein kinase D1/2 is involved in the maturation of multivesicular bodies and secretion of exosomes in T and B lymphocytes

Multivesicular bodies (MVBs) are endocytic compartments that enclose intraluminal vesicles (ILVs) formed by inward budding from the limiting membrane of endosomes. In T lymphocytes, these ILV contain Fas ligand (FasL) and are secreted as 'lethal exosomes' following activation-induced fusio...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Mazzeo, C, Calvo, V, Alonso, R, Mérida, I, Izquierdo, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815981/
https://ncbi.nlm.nih.gov/pubmed/26045048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.72
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