Prognostic importance of CDK4/6-specific activity as a predictive marker for recurrence in patients with endometrial cancer, with or without adjuvant chemotherapy

BACKGROUND: Pathologically low-risk endometrial cancer patients do not receive postoperative treatment; however, 10–15% of these patients show recurrence with poor prognosis. We evaluated the clinical importance of cyclin-dependent kinase 4/6 (CDK4/6) activity, and its significance as a novel biomar...

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Veröffentlicht in:Br J Cancer
Hauptverfasser: Ikeda, Yuji, Oda, Katsutoshi, Ishihara, Hideki, Wada-Hiraike, Osamu, Miyasaka, Aki, Kashiyama, Tomoko, Inaba, Kanako, Fukuda, Tomohiko, Sone, Kenbun, Matsumoto, Yoko, Arimoto, Takahide, Maeda, Daichi, Ikemura, Masako, Fukayama, Masahi, Kawana, Kei, Yano, Tetsu, Aoki, Daisuke, Osuga, Yutaka, Fujii, Tomoyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Molecular Diagnostics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815892/
https://ncbi.nlm.nih.gov/pubmed/26554657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.369
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