A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria

Plasmodium falciparum malaria infection is associated with an early marked increase in plasma von Willebrand factor (VWF) levels, together with a pathological accumulation of hyperreactive ultra-large VWF (UL-VWF) multimers. Given the established critical role of platelets in malaria pathogenesis, t...

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Detalles Bibliográficos
Publicado en:Blood
Main Authors: O’Regan, Niamh, Gegenbauer, Kristina, O’Sullivan, Jamie M., Maleki, Sanaz, Brophy, Teresa M., Dalton, Niall, Chion, Alain, Fallon, Padraic G., Grau, Georges E., Budde, Ulrich, Smith, Owen P., Craig, Alister G., Preston, Roger J. S., O’Donnell, James S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2016
Assuntos:
Thrombosis and Hemostasis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815815/
https://ncbi.nlm.nih.gov/pubmed/26511133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-07-654921
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