A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria

Plasmodium falciparum malaria infection is associated with an early marked increase in plasma von Willebrand factor (VWF) levels, together with a pathological accumulation of hyperreactive ultra-large VWF (UL-VWF) multimers. Given the established critical role of platelets in malaria pathogenesis, t...

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Pubblicato in:Blood
Autori principali: O’Regan, Niamh, Gegenbauer, Kristina, O’Sullivan, Jamie M., Maleki, Sanaz, Brophy, Teresa M., Dalton, Niall, Chion, Alain, Fallon, Padraic G., Grau, Georges E., Budde, Ulrich, Smith, Owen P., Craig, Alister G., Preston, Roger J. S., O’Donnell, James S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2016
Soggetti:
Thrombosis and Hemostasis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815815/
https://ncbi.nlm.nih.gov/pubmed/26511133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-07-654921
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