A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria

Plasmodium falciparum malaria infection is associated with an early marked increase in plasma von Willebrand factor (VWF) levels, together with a pathological accumulation of hyperreactive ultra-large VWF (UL-VWF) multimers. Given the established critical role of platelets in malaria pathogenesis, t...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: O’Regan, Niamh, Gegenbauer, Kristina, O’Sullivan, Jamie M., Maleki, Sanaz, Brophy, Teresa M., Dalton, Niall, Chion, Alain, Fallon, Padraic G., Grau, Georges E., Budde, Ulrich, Smith, Owen P., Craig, Alister G., Preston, Roger J. S., O’Donnell, James S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815815/
https://ncbi.nlm.nih.gov/pubmed/26511133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-07-654921
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