CYP24A1 variant modifies the association between use of oestrogen plus progestogen therapy and colorectal cancer risk

BACKGROUND: Menopausal hormone therapy (MHT) use has been consistently associated with a decreased risk of colorectal cancer (CRC) in women. Our aim was to use a genome-wide gene–environment interaction analysis to identify genetic modifiers of CRC risk associated with use of MHT. METHODS: We includ...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Br J Cancer
Huvudupphovsmän: Garcia-Albeniz, Xabier, Rudolph, Anja, Hutter, Carolyn, White, Emily, Lin, Yi, Rosse, Stephanie A, Figueiredo, Jane C, Harrison, Tabitha A, Jiao, Shuo, Brenner, Hermann, Casey, Graham, Hudson, Thomas J, Thornquist, Mark, Le Marchand, Loic, Potter, John, Slattery, Martha L, Zanke, Brent, Baron, John A, Caan, Bette J, Chanock, Stephen J, Berndt, Sonja I, Stelling, Deanna, Fuchs, Charles S, Hoffmeister, Michael, Butterbach, Katja, Du, Mengmeng, James Gauderman, W, Gunter, Marc J, Lemire, Mathieu, Ogino, Shuji, Lin, Jennifer, Hayes, Richard B, Haile, Robert W, Schoen, Robert E, Warnick, Greg S, Jenkins, Mark A, Thibodeau, Stephen N, Schumacher, Fredrick R, Lindor, Noralane M, Kolonel, Laurence N, Hopper, John L, Gong, Jian, Seminara, Daniela, Pflugeisen, Bethann M, Ulrich, Cornelia M, Qu, Conghui, Duggan, David, Cotterchio, Michelle, Campbell, Peter T, Carlson, Christopher S, Newcomb, Polly A, Giovannucci, Edward, Hsu, Li, Chan, Andrew T, Peters, Ulrike, Chang-Claude, Jenny
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Genetics & Genomics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815813/
https://ncbi.nlm.nih.gov/pubmed/26766742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.443
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk