CYP24A1 variant modifies the association between use of oestrogen plus progestogen therapy and colorectal cancer risk

BACKGROUND: Menopausal hormone therapy (MHT) use has been consistently associated with a decreased risk of colorectal cancer (CRC) in women. Our aim was to use a genome-wide gene–environment interaction analysis to identify genetic modifiers of CRC risk associated with use of MHT. METHODS: We includ...

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書誌詳細
出版年:Br J Cancer
主要な著者: Garcia-Albeniz, Xabier, Rudolph, Anja, Hutter, Carolyn, White, Emily, Lin, Yi, Rosse, Stephanie A, Figueiredo, Jane C, Harrison, Tabitha A, Jiao, Shuo, Brenner, Hermann, Casey, Graham, Hudson, Thomas J, Thornquist, Mark, Le Marchand, Loic, Potter, John, Slattery, Martha L, Zanke, Brent, Baron, John A, Caan, Bette J, Chanock, Stephen J, Berndt, Sonja I, Stelling, Deanna, Fuchs, Charles S, Hoffmeister, Michael, Butterbach, Katja, Du, Mengmeng, James Gauderman, W, Gunter, Marc J, Lemire, Mathieu, Ogino, Shuji, Lin, Jennifer, Hayes, Richard B, Haile, Robert W, Schoen, Robert E, Warnick, Greg S, Jenkins, Mark A, Thibodeau, Stephen N, Schumacher, Fredrick R, Lindor, Noralane M, Kolonel, Laurence N, Hopper, John L, Gong, Jian, Seminara, Daniela, Pflugeisen, Bethann M, Ulrich, Cornelia M, Qu, Conghui, Duggan, David, Cotterchio, Michelle, Campbell, Peter T, Carlson, Christopher S, Newcomb, Polly A, Giovannucci, Edward, Hsu, Li, Chan, Andrew T, Peters, Ulrike, Chang-Claude, Jenny
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
Genetics & Genomics
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815813/
https://ncbi.nlm.nih.gov/pubmed/26766742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.443
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