Endothelin

The endothelins comprise three structurally similar 21-amino acid peptides. Endothelin-1 and -2 activate two G-protein coupled receptors, ET(A) and ET(B), with equal affinity, whereas endothelin-3 has a lower affinity for the ET(A) subtype. Genes encoding the peptides are present only among vertebra...

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Detalhes bibliográficos
Publicado no:Pharmacol Rev
Main Authors: Davenport, Anthony P., Hyndman, Kelly A., Dhaun, Neeraj, Southan, Christopher, Kohan, Donald E., Pollock, Jennifer S., Pollock, David M., Webb, David J., Maguire, Janet J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2016
Assuntos:
Review Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815360/
https://ncbi.nlm.nih.gov/pubmed/26956245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.115.011833
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