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Endothelin antagonists for diabetic and non-diabetic chronic kidney disease
Numerous pre-clinical studies have implicated endothelin-1 in the pathogenesis of diabetic and non-diabetic chronic kidney disease (CKD). Renal endothelin-1 production is almost universally increased in kidney disease. The pathologic effects of endothelin-1, including vasoconstriction, proteinuria,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3791980/ https://ncbi.nlm.nih.gov/pubmed/23228194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12064 |
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