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Endothelin antagonists for diabetic and non-diabetic chronic kidney disease

Numerous pre-clinical studies have implicated endothelin-1 in the pathogenesis of diabetic and non-diabetic chronic kidney disease (CKD). Renal endothelin-1 production is almost universally increased in kidney disease. The pathologic effects of endothelin-1, including vasoconstriction, proteinuria,...

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Détails bibliographiques
Auteurs principaux: Kohan, Donald E, Pollock, David M
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791980/
https://ncbi.nlm.nih.gov/pubmed/23228194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12064
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