Distinct Actions of Endothelin A-Selective Versus Combined Endothelin A/B Receptor Antagonists in Early Diabetic Kidney Disease

Selective endothelin A (ET(A)) and combined ET(A) and ET(B) receptor antagonists are being investigated for use in treating diabetic nephropathy. However, the receptor-specific mechanisms responsible for producing the potential benefits have not been discerned. Thus, we determined the actions of ET(...

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Bibliographic Details
Main Authors: Saleh, Mohamed A., Pollock, Jennifer S., Pollock, David M.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2011
Subjects:
Gastrointestinal, Hepatic, Pulmonary, and Renal
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126640/
https://ncbi.nlm.nih.gov/pubmed/21471190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.178988
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