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The Role of Endothelin and Endothelin Antagonists in Chronic Kidney Disease

BACKGROUND: Endothelins (ET) are a family of peptides that act as potent vasoconstrictors and pro-fibrotic growth factors. ET-1 is integral to renal and cardiovascular pathophysiology and exerts effects via autocrine, paracrine and endocrine signaling pathways tied to regulation of aldosterone, cate...

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Detalhes bibliográficos
Publicado no:Kidney Dis (Basel)
Main Authors: Raina, Rupesh, Chauvin, Abigail, Chakraborty, Ronith, Nair, Nikhil, Shah, Haikoo, Krishnappa, Vinod, Kusumi, Kirsten
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995952/
https://ncbi.nlm.nih.gov/pubmed/32021871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000504623
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