Carregant...
Destabilization of the dimer interface is a common consequence of diverse ALS‐associated mutations in metal free SOD1
Neurotoxic misfolding of Cu, Zn‐superoxide dismutase (SOD1) is implicated in causing amyotrophic lateral sclerosis, a devastating and incurable neurodegenerative disease. Disease‐linked mutations in SOD1 have been proposed to promote misfolding and aggregation by decreasing protein stability and inc...
Guardat en:
| Publicat a: | Protein Sci |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2015
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4815230/ https://ncbi.nlm.nih.gov/pubmed/26362407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2803 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|