A porcine model of osteosarcoma

We previously produced pigs with a latent oncogenic TP53 mutation. Humans with TP53 germline mutations are predisposed to a wide spectrum of early-onset cancers, predominantly breast, brain, adrenal gland cancer, soft tissue sarcomas and osteosarcomas. Loss of p53 function has been observed in >5...

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Bibliografski detalji
Izdano u:Oncogenesis
Glavni autori: Saalfrank, A, Janssen, K-P, Ravon, M, Flisikowski, K, Eser, S, Steiger, K, Flisikowska, T, Müller-Fliedner, P, Schulze, É, Brönner, C, Gnann, A, Kappe, E, Böhm, B, Schade, B, Certa, U, Saur, D, Esposito, I, Kind, A, Schnieke, A
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815050/
https://ncbi.nlm.nih.gov/pubmed/26974205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2016.19
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