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A porcine model of osteosarcoma
We previously produced pigs with a latent oncogenic TP53 mutation. Humans with TP53 germline mutations are predisposed to a wide spectrum of early-onset cancers, predominantly breast, brain, adrenal gland cancer, soft tissue sarcomas and osteosarcomas. Loss of p53 function has been observed in >5...
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| Veröffentlicht in: | Oncogenesis |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4815050/ https://ncbi.nlm.nih.gov/pubmed/26974205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2016.19 |
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