HIPK2 overexpression leads to stabilization of p53 protein and increased p53 transcriptional activity by decreasing Mdm2 protein levels

BACKGROUND: HIPK2 (homeodomain-interacting protein kinase 2) has been identified as a nuclear serine/threonine kinase. A central function of HIPK2 is repressing transcription of homeodomain containing transcription factors. RESULTS AND CONCLUSIONS: We show here that HIPK2 activates transcription med...

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Detalhes bibliográficos

Publicado no:	BMC Mol Biol
Principais autores:	Wang, Ying, Debatin, Klaus-Michael, Hug, Hubert
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2001
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48146/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11532197/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2199-2-8
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