HIPK2 overexpression leads to stabilization of p53 protein and increased p53 transcriptional activity by decreasing Mdm2 protein levels

BACKGROUND: HIPK2 (homeodomain-interacting protein kinase 2) has been identified as a nuclear serine/threonine kinase. A central function of HIPK2 is repressing transcription of homeodomain containing transcription factors. RESULTS AND CONCLUSIONS: We show here that HIPK2 activates transcription med...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Wang, Ying, Debatin, Klaus-Michael, Hug, Hubert
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2001
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC48146/
https://ncbi.nlm.nih.gov/pubmed/11532197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-2-8
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker