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Challenging nickel-catalysed amine arylations enabled by tailored ancillary ligand design

Palladium-catalysed C(sp(2))–N cross-coupling (that is, Buchwald–Hartwig amination) is employed widely in synthetic chemistry, including in the pharmaceutical industry, for the synthesis of (hetero)aniline derivatives. However, the cost and relative scarcity of palladium provides motivation for the...

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Publicat a:Nat Commun
Autors principals: Lavoie, Christopher M., MacQueen, Preston M., Rotta-Loria, Nicolas L., Sawatzky, Ryan S., Borzenko, Andrey, Chisholm, Alicia J., Hargreaves, Breanna K. V., McDonald, Robert, Ferguson, Michael J., Stradiotto, Mark
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814586/
https://ncbi.nlm.nih.gov/pubmed/27004442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11073
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