Experimental and Metabolic Modeling Evidence for a Folate-Cleaving Side-Activity of Ketopantoate Hydroxymethyltransferase (PanB)

Tetrahydrofolate (THF) and its one-carbon derivatives, collectively termed folates, are essential cofactors, but are inherently unstable. While it is clear that chemical oxidation can cleave folates or damage their pterin precursors, very little is known about enzymatic damage to these molecules or...

詳細記述

保存先:
書誌詳細
出版年:Front Microbiol
主要な著者: Thiaville, Jennifer J., Frelin, Océane, García-Salinas, Carolina, Harrison, Katherine, Hasnain, Ghulam, Horenstein, Nicole A., Díaz de la Garza, Rocio I., Henry, Christopher S., Hanson, Andrew D., de Crécy-Lagard, Valérie
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2016
主題:
Microbiology
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814558/
https://ncbi.nlm.nih.gov/pubmed/27065985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.00431
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