Semicontinuous Bioreactor Production of Recombinant Butyrylcholinesterase in Transgenic Rice Cell Suspension Cultures

An active and tetrameric form of recombinant butyrylcholinesterase (BChE), a large and complex human enzyme, was produced via semicontinuous operation in a transgenic rice cell suspension culture. After transformation of rice callus and screening of transformants, the cultures were scaled up from cu...

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Publicado en:Front Plant Sci
Autores principales: Corbin, Jasmine M., Hashimoto, Bryce I., Karuppanan, Kalimuthu, Kyser, Zachary R., Wu, Liying, Roberts, Brian A., Noe, Amy R., Rodriguez, Raymond L., McDonald, Karen A., Nandi, Somen
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2016
Materias:
Plant Science
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814504/
https://ncbi.nlm.nih.gov/pubmed/27066048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpls.2016.00412
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