Assignment of Functional Relevance to Genes at Type 2 Diabetes-Associated Loci Through Investigation of β-Cell Mass Deficits

Type 2 diabetes (T2D) has been associated with a large number of genomic loci, many of which encompass multiple genes without a definitive causal gene. This complexity has hindered efforts to clearly identify functional candidate genes and interpret their role in mediating susceptibility to disease....

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Bibliographic Details
Published in:Mol Endocrinol
Main Authors: O'Hare, Elizabeth A., Yerges-Armstrong, Laura M., Perry, James A., Shuldiner, Alan R., Zaghloul, Norann A.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2016
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814477/
https://ncbi.nlm.nih.gov/pubmed/26963759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1243
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