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Combination of Pim kinase inhibitors and Bcl-2 antagonists in chronic lymphocytic leukemia cells

The Pim proteins are Ser/Thr kinases overexpressed in several hematological malignancies such as chronic lymphocytic leukemia (CLL) and some solid cancers like prostate cancer. Several small molecules have been developed to inhibit these kinases. In prostate cancer cell lines, the Pim kinase inhibit...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Leuk Lymphoma
Prif Awduron: Cervantes-Gomez, Fabiola, Lavergne, Bethany, Keating, Michael J., Wierda, William G., Gandhi, Varsha
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814351/
https://ncbi.nlm.nih.gov/pubmed/26088877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2015.1063141
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