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Binomial mixture model-based association testing to account for genetic heterogeneity for GWAS
Genome-wide association studies (GWASs) have confirmed the ubiquitous existence of genetic heterogeneity for common disease: multiple common genetic variants have been identified to be associated, while many more are yet expected to be uncovered. On the other hand, the single SNP-based trend test (o...
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| Publicado en: | Genet Epidemiol |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4814320/ https://ncbi.nlm.nih.gov/pubmed/26916514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21954 |
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