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Binomial Mixture Model-based Association Tests under Genetic Heterogeneity
Most of the existing association tests for population-based case-control studies are based on comparing the mean genotype scores between the case and control groups, which may not be efficient under genetic heterogeneity. Given that most common diseases are genetically heterogeneous, caused by mutat...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3354651/ https://ncbi.nlm.nih.gov/pubmed/19725835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2009.00542.x |
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