The Hemagglutinin of Bat-Associated Influenza Viruses Is Activated by TMPRSS2 for pH-Dependent Entry into Bat but Not Human Cells

New World bats have recently been discovered to harbor influenza A virus (FLUAV)-related viruses, termed bat-associated influenza A-like viruses (batFLUAV). The internal proteins of batFLUAV are functional in mammalian cells. In contrast, no biological functionality could be demonstrated for the sur...

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Vydáno v:PLoS One
Hlavní autoři: Hoffmann, Markus, Krüger, Nadine, Zmora, Pawel, Wrensch, Florian, Herrler, Georg, Pöhlmann, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814062/
https://ncbi.nlm.nih.gov/pubmed/27028521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152134
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