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Control of Foxp3 stability through modulation of TET activity
Ten-eleven translocation (TET) enzymes oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine and other oxidized methylcytosines, intermediates in DNA demethylation. In this study, we examine the role of TET proteins in regulating Foxp3, a transcription factor essential for the development and fu...
Tallennettuna:
Julkaisussa: | J Exp Med |
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Päätekijät: | , , , , , , , , , , , |
Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
The Rockefeller University Press
2016
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4813667/ https://ncbi.nlm.nih.gov/pubmed/26903244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151438 |
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