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Activated mast cells synthesize and release soluble ST2-a decoy receptor for IL-33

Interleukin 33 (IL-33) released from damaged cells plays a central role in allergic inflammation by acting through its membrane-bound receptor, ST2 receptor (ST2L). IL-33 activity can be neutralized by the soluble spliced variant of ST2 (sST2) which has been associated with allergic inflammation but...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Bandara, Geethani, Beaven, Michael A., Olivera, Ana, Gilfillan, Alasdair M., Metcalfe, Dean D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813659/
https://ncbi.nlm.nih.gov/pubmed/26256265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545501
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