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The Ankrd13 Family of Ubiquitin-interacting Motif-bearing Proteins Regulates Valosin-containing Protein/p97 Protein-mediated Lysosomal Trafficking of Caveolin 1

Caveolin 1 (Cav-1) is an oligomeric protein that forms flask-shaped, lipid-rich pits, termed caveolae, on the plasma membrane. Cav-1 is targeted for lysosomal degradation in ubiquitination- and valosin-containing protein (VCP)-dependent manners. VCP, an ATPase associated with diverse cellular activi...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Burana, Daocharad, Yoshihara, Hidehito, Tanno, Hidetaka, Yamamoto, Akitsugu, Saeki, Yasushi, Tanaka, Keiji, Komada, Masayuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813590/
https://ncbi.nlm.nih.gov/pubmed/26797118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.710707
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