Rapid Remodeling of Invadosomes by G(i)-coupled Receptors: DISSECTING THE ROLE OF Rho GTPases

Invadosomes are actin-rich membrane protrusions that degrade the extracellular matrix to drive tumor cell invasion. Key players in invadosome formation are c-Src and Rho family GTPases. Invadosomes can reassemble into circular rosette-like superstructures, but the underlying signaling mechanisms rem...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Kedziora, Katarzyna M., Leyton-Puig, Daniela, Argenzio, Elisabetta, Boumeester, Anja J., van Butselaar, Bram, Yin, Taofei, Wu, Yi I., van Leeuwen, Frank N., Innocenti, Metello, Jalink, Kees, Moolenaar, Wouter H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813461/
https://ncbi.nlm.nih.gov/pubmed/26740622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.695940
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