Characterization of 12 GnRH peptide agonists – a kinetic perspective

BACKGROUND AND PURPOSE: Drug‐target residence time is an important, yet often overlooked, parameter in drug discovery. Multiple studies have proposed an increased residence time to be beneficial for improved drug efficacy and/or longer duration of action. Currently, there are many drugs on the marke...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Nederpelt, Indira, Georgi, Victoria, Schiele, Felix, Nowak‐Reppel, Katrin, Fernández‐Montalván, Amaury E., IJzerman, Adriaan P., Heitman, Laura H.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813373/
https://ncbi.nlm.nih.gov/pubmed/26398856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13342
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