Coordination of autophagosome–lysosome fusion and transport by a Klp98A–Rab14 complex in Drosophila

Degradation of cellular material by autophagy is essential for cell survival and homeostasis, and requires intracellular transport of autophagosomes to encounter acidic lysosomes through unknown mechanisms. Here, we identify the PX-domain-containing kinesin Klp98A as a new regulator of autophagosome...

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Pubblicato in:J Cell Sci
Autori principali: Mauvezin, Caroline, Neisch, Amanda L., Ayala, Carlos I., Kim, Jung, Beltrame, Abigail, Braden, Christopher R., Gardner, Melissa K., Hays, Thomas S., Neufeld, Thomas P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813314/
https://ncbi.nlm.nih.gov/pubmed/26763909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.175224
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