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Coordination of autophagosome–lysosome fusion and transport by a Klp98A–Rab14 complex in Drosophila

Degradation of cellular material by autophagy is essential for cell survival and homeostasis, and requires intracellular transport of autophagosomes to encounter acidic lysosomes through unknown mechanisms. Here, we identify the PX-domain-containing kinesin Klp98A as a new regulator of autophagosome...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Mauvezin, Caroline, Neisch, Amanda L., Ayala, Carlos I., Kim, Jung, Beltrame, Abigail, Braden, Christopher R., Gardner, Melissa K., Hays, Thomas S., Neufeld, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813314/
https://ncbi.nlm.nih.gov/pubmed/26763909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.175224
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