Coordination of autophagosome–lysosome fusion and transport by a Klp98A–Rab14 complex in Drosophila

Degradation of cellular material by autophagy is essential for cell survival and homeostasis, and requires intracellular transport of autophagosomes to encounter acidic lysosomes through unknown mechanisms. Here, we identify the PX-domain-containing kinesin Klp98A as a new regulator of autophagosome...

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Detaylı Bibliyografya
Yayımlandı:J Cell Sci
Asıl Yazarlar: Mauvezin, Caroline, Neisch, Amanda L., Ayala, Carlos I., Kim, Jung, Beltrame, Abigail, Braden, Christopher R., Gardner, Melissa K., Hays, Thomas S., Neufeld, Thomas P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists Ltd 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813314/
https://ncbi.nlm.nih.gov/pubmed/26763909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.175224
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