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Wnt/β-catenin signaling enables developmental transitions during valvulogenesis
Heart valve development proceeds through coordinated steps by which endocardial cushions (ECs) form thin, elongated and stratified valves. Wnt signaling and its canonical effector β-catenin are proposed to contribute to endocardial-to-mesenchymal transformation (EMT) through postnatal steps of valvu...
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| Publié dans: | Development |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Company of Biologists Ltd
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4813288/ https://ncbi.nlm.nih.gov/pubmed/26893350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.130575 |
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