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Wnt/β-catenin signaling enables developmental transitions during valvulogenesis

Heart valve development proceeds through coordinated steps by which endocardial cushions (ECs) form thin, elongated and stratified valves. Wnt signaling and its canonical effector β-catenin are proposed to contribute to endocardial-to-mesenchymal transformation (EMT) through postnatal steps of valvu...

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Detalles Bibliográficos
Publicado en:Development
Main Authors: Bosada, Fernanda M., Devasthali, Vidusha, Jones, Kimberly A., Stankunas, Kryn
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists Ltd 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813288/
https://ncbi.nlm.nih.gov/pubmed/26893350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.130575
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