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Wnt/β-catenin signaling enables developmental transitions during valvulogenesis

Heart valve development proceeds through coordinated steps by which endocardial cushions (ECs) form thin, elongated and stratified valves. Wnt signaling and its canonical effector β-catenin are proposed to contribute to endocardial-to-mesenchymal transformation (EMT) through postnatal steps of valvu...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Bosada, Fernanda M., Devasthali, Vidusha, Jones, Kimberly A., Stankunas, Kryn
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813288/
https://ncbi.nlm.nih.gov/pubmed/26893350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.130575
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