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Wnt/β-catenin signaling enables developmental transitions during valvulogenesis

Heart valve development proceeds through coordinated steps by which endocardial cushions (ECs) form thin, elongated and stratified valves. Wnt signaling and its canonical effector β-catenin are proposed to contribute to endocardial-to-mesenchymal transformation (EMT) through postnatal steps of valvu...

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Publicat a:Development
Autors principals: Bosada, Fernanda M., Devasthali, Vidusha, Jones, Kimberly A., Stankunas, Kryn
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813288/
https://ncbi.nlm.nih.gov/pubmed/26893350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.130575
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