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Wnt/β-catenin signaling enables developmental transitions during valvulogenesis
Heart valve development proceeds through coordinated steps by which endocardial cushions (ECs) form thin, elongated and stratified valves. Wnt signaling and its canonical effector β-catenin are proposed to contribute to endocardial-to-mesenchymal transformation (EMT) through postnatal steps of valvu...
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Publicado no: | Development |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Company of Biologists Ltd
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4813288/ https://ncbi.nlm.nih.gov/pubmed/26893350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.130575 |
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