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Mammary epithelial tubes elongate through MAPK-dependent coordination of cell migration

Mammary branching morphogenesis is regulated by receptor tyrosine kinases (RTKs). We sought to determine how these RTK signals alter proliferation and migration to accomplish tube elongation in mouse. Both behaviors occur but it has been difficult to determine their relative contribution to elongati...

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Bibliografiske detaljer
Udgivet i:Development
Main Authors: Huebner, Robert J., Neumann, Neil M., Ewald, Andrew J.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813284/
https://ncbi.nlm.nih.gov/pubmed/26839364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.127944
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