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Collective Epithelial Migration and Cell Rearrangements Drive Mammary Branching Morphogenesis

Epithelial organs are built through the movement of groups of interconnected cells. We observed cells in elongating mammary ducts reorganize into a multilayered epithelium, migrate collectively, and rearrange dynamically, all without forming leading cellular extensions. Duct initiation required prol...

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Detalhes bibliográficos
Main Authors: Ewald, Andrew J., Brenot, Audrey, Duong, Myhanh, Chan, Bianca S., Werb, Zena
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773823/
https://ncbi.nlm.nih.gov/pubmed/18410732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.03.003
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