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Collective Epithelial Migration and Cell Rearrangements Drive Mammary Branching Morphogenesis

Epithelial organs are built through the movement of groups of interconnected cells. We observed cells in elongating mammary ducts reorganize into a multilayered epithelium, migrate collectively, and rearrange dynamically, all without forming leading cellular extensions. Duct initiation required prol...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ewald, Andrew J., Brenot, Audrey, Duong, Myhanh, Chan, Bianca S., Werb, Zena
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773823/
https://ncbi.nlm.nih.gov/pubmed/18410732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.03.003
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