Identification of Toxic Pyrrolizidine Alkaloids and Their Common Hepatotoxicity Mechanism

Pyrrolizidine Alkaloids (PAs) are currently one of the most important botanical hepatotoxic ingredients. Glutathion (GSH) metabolism is the most reported pathway involved in hepatotoxicity mechanism of PAs. We speculate that, for different PAs, there should be a common mechanism underlying their hep...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Yan, Xinmiao, Kang, Hong, Feng, Jun, Yang, Yiyan, Tang, Kailin, Zhu, Ruixin, Yang, Li, Wang, Zhengtao, Cao, Zhiwei
Format: Artigo
Language:Inglês
Published: MDPI 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813181/
https://ncbi.nlm.nih.gov/pubmed/26959016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17030318
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