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Identification of Toxic Pyrrolizidine Alkaloids and Their Common Hepatotoxicity Mechanism

Pyrrolizidine Alkaloids (PAs) are currently one of the most important botanical hepatotoxic ingredients. Glutathion (GSH) metabolism is the most reported pathway involved in hepatotoxicity mechanism of PAs. We speculate that, for different PAs, there should be a common mechanism underlying their hep...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Yan, Xinmiao, Kang, Hong, Feng, Jun, Yang, Yiyan, Tang, Kailin, Zhu, Ruixin, Yang, Li, Wang, Zhengtao, Cao, Zhiwei
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813181/
https://ncbi.nlm.nih.gov/pubmed/26959016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17030318
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