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Overcoming heterologous protein interdependency to optimize P450-mediated Taxol precursor synthesis in Escherichia coli

Recent advances in metabolic engineering have demonstrated the potential to exploit biological chemistry for the synthesis of complex molecules. Much of the progress to date has leveraged increasingly precise genetic tools to control the transcription and translation of enzymes for superior biosynth...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Main Authors: Biggs, Bradley Walters, Lim, Chin Giaw, Sagliani, Kristen, Shankar, Smriti, Stephanopoulos, Gregory, De Mey, Marjan, Ajikumar, Parayil Kumaran
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812725/
https://ncbi.nlm.nih.gov/pubmed/26951651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515826113
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