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Microscopic interpretation of folding ϕ-values using the transition path ensemble

All-atom molecular dynamics simulations now allow us to create movies of proteins folding and unfolding. However, it is difficult to assess the accuracy of the folding mechanisms observed because experiments cannot yet directly resolve events occurring along the transition paths between unfolded and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Best, Robert B., Hummer, Gerhard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812701/
https://ncbi.nlm.nih.gov/pubmed/26957599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520864113
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