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Network-level effects of kinase inhibitors modulate TNF-α-induced apoptosis in the intestinal epithelium
Individual signaling pathways are not isolated, but rather operate in the context of the broader signaling network. Thus, the response of a cell to perturbation of a given pathway depends on the state of the network, which depends upon contextual inputs from the microenvironment. The cytokine tumor...
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| Publicado no: | Sci Signal |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4812576/ https://ncbi.nlm.nih.gov/pubmed/26671150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aac7235 |
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