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Development of an Optimized Protocol for NMR Metabolomics Studies of Human Colon Cancer Cell Lines and First Insight from Testing of the Protocol Using DNA G-Quadruplex Ligands as Novel Anti-Cancer Drugs

The study of cell lines by nuclear magnetic resonance (NMR) spectroscopy metabolomics represents a powerful tool to understand how the local metabolism and biochemical pathways are influenced by external or internal stimuli. In particular, the use of adherent mammalian cells is emerging in the metab...

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Détails bibliographiques
Publié dans:Metabolites
Auteurs principaux: Lauri, Ilaria, Savorani, Francesco, Iaccarino, Nunzia, Zizza, Pasquale, Pavone, Luigi Michele, Novellino, Ettore, Engelsen, Søren Balling, Randazzo, Antonio
Format: Artigo
Langue:Inglês
Publié: MDPI 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812333/
https://ncbi.nlm.nih.gov/pubmed/26784246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo6010004
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