Granulocyte colony-stimulating factor (G-CSF): A saturated fatty acid-induced myokine with insulin-desensitizing properties in humans

OBJECTIVE: Circulating long-chain free fatty acids (FFAs) are important metabolic signals that acutely enhance fatty acid oxidation, thermogenesis, energy expenditure, and insulin secretion. However, if chronically elevated, they provoke inflammation, insulin resistance, and β-cell failure. Moreover...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Ordelheide, Anna-Maria, Gommer, Nadja, Böhm, Anja, Hermann, Carina, Thielker, Inga, Machicao, Fausto, Fritsche, Andreas, Stefan, Norbert, Häring, Hans-Ulrich, Staiger, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812007/
https://ncbi.nlm.nih.gov/pubmed/27069870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.02.001
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