Granulocyte colony-stimulating factor (G-CSF): A saturated fatty acid-induced myokine with insulin-desensitizing properties in humans

OBJECTIVE: Circulating long-chain free fatty acids (FFAs) are important metabolic signals that acutely enhance fatty acid oxidation, thermogenesis, energy expenditure, and insulin secretion. However, if chronically elevated, they provoke inflammation, insulin resistance, and β-cell failure. Moreover...

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Библиографические подробности
Опубликовано в: :Mol Metab
Главные авторы: Ordelheide, Anna-Maria, Gommer, Nadja, Böhm, Anja, Hermann, Carina, Thielker, Inga, Machicao, Fausto, Fritsche, Andreas, Stefan, Norbert, Häring, Hans-Ulrich, Staiger, Harald
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2016
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812007/
https://ncbi.nlm.nih.gov/pubmed/27069870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.02.001
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