Granulocyte colony-stimulating factor (G-CSF): A saturated fatty acid-induced myokine with insulin-desensitizing properties in humans

OBJECTIVE: Circulating long-chain free fatty acids (FFAs) are important metabolic signals that acutely enhance fatty acid oxidation, thermogenesis, energy expenditure, and insulin secretion. However, if chronically elevated, they provoke inflammation, insulin resistance, and β-cell failure. Moreover...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Metab
Auteurs principaux: Ordelheide, Anna-Maria, Gommer, Nadja, Böhm, Anja, Hermann, Carina, Thielker, Inga, Machicao, Fausto, Fritsche, Andreas, Stefan, Norbert, Häring, Hans-Ulrich, Staiger, Harald
Format: Artigo
Langue:Inglês
Publié: Elsevier 2016
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812007/
https://ncbi.nlm.nih.gov/pubmed/27069870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.02.001
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