Common variation in the sodium/glucose cotransporter 2 gene SLC5A2 does neither affect fasting nor glucose-suppressed plasma glucagon concentrations

AIM: Inhibition of sodium/glucose cotransporter 2 (SGLT2), the key transport protein in renal glucose reabsorption, promotes glucose excretion and represents a new concept in the therapy of type-2 diabetes. In addition, SGLT2 inhibition elevates circulating glucagon concentrations and enhances hepat...

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Vydáno v:PLoS One
Hlavní autoři: Ordelheide, Anna-Maria, Böhm, Anja, Kempe-Teufel, Daniela, Wagner, Robert, Machicao, Fausto, Heni, Martin, Stefan, Norbert, Fritsche, Andreas, Häring, Hans-Ulrich, Staiger, Harald
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417681/
https://ncbi.nlm.nih.gov/pubmed/28472182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177148
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