Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes

Embryonal Rhabdomyosarcoma (ERMS) and Undifferentiated Pleomorphic Sarcoma (UPS) are distinct sarcoma subtypes. Here we investigate the relevance of the satellite cell (SC) niche in sarcoma development by using Hepatocyte Growth Factor (HGF) to perturb the niche microenvironment. In a Pax7 wild type...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:eLife
मुख्य लेखकों: Morena, Deborah, Maestro, Nicola, Bersani, Francesca, Forni, Paolo Emanuele, Lingua, Marcello Francesco, Foglizzo, Valentina, Šćepanović, Petar, Miretti, Silvia, Morotti, Alessandro, Shern, Jack F, Khan, Javed, Ala, Ugo, Provero, Paolo, Sala, Valentina, Crepaldi, Tiziana, Gasparini, Patrizia, Casanova, Michela, Ferrari, Andrea, Sozzi, Gabriella, Chiarle, Roberto, Ponzetto, Carola, Taulli, Riccardo
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: eLife Sciences Publications, Ltd 2016
विषय:
Cell Biology
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811764/
https://ncbi.nlm.nih.gov/pubmed/26987019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12116
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